Related: Governance | DOGE | America's AI Vision | AI Action Plan
President Donald Trump signed an executive order on Monday, November 24, establishing the "Genesis Mission," a federal effort to boost innovation using artificial intelligence, the latest step by the administration to promote AI technology and its adoption. The effort aims to better coordinate research done by agencies across the government and more effectively integrate AI tools to achieve more scientific breakthroughs.

The mission will harness the computing resources of the Department of Energy's national labs to tap federal datasets and enable more experiments utilizing AI, Kratsios added, predicting the effort would help shorten the timelines for scientific discoveries.
Partnerships with private-sector companies, including Nvidia Corp., Dell Technologies Inc., HPE, and Advanced Micro Devices Inc., will boost supercomputing resources at the labs, according to a senior administration official, who spoke on condition of anonymity t provide details on the order. The official cited recent announcements from those companies as a model for potential new ones. Officials on Monday said the push would accelerate scientific discoveries in materials engineering, health sciences and energy. And they sought to cast the innovation gains as critical to helping bolster production and lower prices, another key priority for the administration as it seeks to address voter concerns about living costs.
The massive computing resources needed for AI's development and use rely on energy-hungry data centers, which has spurred worries that the adoption of the technology will only increase strains on the US electric grid. Energy Secretary Chris Wright on Monday said the Genesis initiative would help counter rising energy costs, saying one of its "ultimate goals" in the energy space is to "bring more energy on, make our electricity grid more efficient and reverse price rises that have infuriated American citizens."
"We're going to stop the rise of price of energy. First, it'll plateau, and ultimately will push downward pressure on the prices of electricity," Wright said.
The initiative was previewed earlier in November by Department of Energy Chief of Staff Carl Coe, who cast it as an effort to signal that the Trump administration sees the race to develop AI technology as just as important as the space race and the World War II-era Manhattan Project to develop the atomic bomb. Kratsios on Monday called it the "largest marshaling of federal scientific resources since the Apollo program," the US mission to send humans to the moon and bring them back to Earth safely.
Trump has frequently hailed the promise of AI and made its development a top priority for his administration, pushing policies he says are critical to ensuring the US wins a race with China and others to advance the technology. Through a host of executive orders, Trump has moved to ease regulatory burdens to make it easier for companies to build AI infrastructure and power data centers and for allies to obtain key hardware and software. He's also pushed to block state-level regulation in the US, arguing for a federal standard. The president is preparing an executive order that would allow the Department of Justice to sue states over artificial intelligence regulations it deems unconstitutional.
Today, President Donald J. Trump signed an Executive Order launching the Genesis Mission, a new national effort to use artificial intelligence (AI) to transform how scientific research is conducted and accelerate the speed of scientific discovery. The Genesis Mission charges the Secretary of Energy with leveraging our National Laboratories to unite America's brightest minds, most powerful computers, and vast scientific data into one cooperative system for research.
The Order directs the Department of Energy to create a closed-loop AI experimentation platform that integrates our Nation's world-class supercomputers and unique data assets to generate scientific foundation models and power robotic laboratories. The Order instructs the Assistant to the President for Science and Technology (APST) to coordinate the national initiative and the integration of data and infrastructure from across the Federal government. The Secretary of Energy, APST, and the Special Advisor for AI & Crypto will collaborate with academia and private-sector innovators to support and enhance the Genesis Mission.
Priority areas of focus include the greatest scientific challenges of our time that can dramatically improve our Nation's national, economic, and health security, including biotechnology, critical materials, nuclear fission and fusion energy, space exploration, quantum information science, and semiconductors and microelectronics.
With the Genesis Mission, the Trump Administration intends to dramatically expand the productivity and impact of Federal research and development within a decade. Despite research budgets soaring since the 1990s, scientific progress has stalled, new drug approvals have declined, and more researchers are needed to achieve the same outputs.
Harnessing AI as a scientific tool will revolutionize the way scientific research is conducted. For example, AI technologies can generate models of protein structures and novel materials, design and analyze experiments, and aggregate and generate new data faster and more effectively. Research that once took years could now take weeks or months. To do this, AI needs large amounts of organized and high-quality data and significant computing power. These datasets and computing technology already exist within DOE's National Laboratories. With the Genesis Mission, the Trump Administration is bringing the power of AI to bear on our already expansive data infrastructure and creating a platform for multiple Federal research agencies and the private sector to collaborate to achieve breakthroughs currently thought impossible, and to win and stay ahead in the AI race.
President Trump continues to prioritize America's global dominance in AI to usher in a new golden age of human flourishing, economic competitiveness, and national security.
In January, President Trump signed an Executive Order to reverse harmful Biden Administration AI policies and enhance America's global AI dominance.
In April, President Trump signed an Executive Order to advance AI education for America's youth.
In July, President Trump signed Executive Orders to prevent woke AI in the Federal government and promote the export of full-stack American AI technologies.
In July, President Trump issued America's AI Action Plan, a policy agenda identifying nearly a hundred Federal actions to accelerate American AI innovation, build AI infrastructure at home, and lead in international diplomacy and security.
The AI Action Plan includes recommended policies for investing in AI-enabled science, including the direction to build world-class data sets.
In September, the President signed an Executive Order on harnessing AI innovation to unlock cures for pediatric cancer, using the Childhood Cancer Data Initiative, which President Trump initially established in 2019 to collect, generate, and analyze childhood cancer data.